The striking feature of cancer therapy once cancer is framed as a metabolic disease is the combinatorial synergy observed. We have observed the synergistic efficacy when the ketogenic diet is combined with radiation, cisplatin, 2DG, and now hyperbaric oxygen therapy. Here is a link to the study.
Dr. George W. Yu, M.D. of Aegis Medical and Research Associates, clinical professor of Urology, George Washington University Medical Center not only researches the effects of a restricted calorie diet on cancer, he lives it. Dr. Yu practices the diet right along side the numerous patients that he treats with it — his dedication and […]
http://videocast.nih.gov/summary.asp?live=7542 The above link is of Dr. Peter Pedersen in a NIH/NCI presentation on the exploitation of hexokinase II by 3-BP. Dr. Pedersen is an exemplary research scientist who is doing the ‘heavy-lifting’, the gritty, molecular details of cancer’s defective metabolism. When you watch the video it is impossible to not get excited about this […]
Angelina Jolie’s May 14th op-ed in the New York times about her recent preventative double mastectomy was touching, courageous, and informative. Most remain unaware of genetic predispositions to cancer including the BRAC1 gene. The fact is, inherited mutations that result in an increased predisposition to acquire cancer are rare. Only 5 to 7 percent of […]
As an Assistant Professor at the University of South Florida since 2008, D’Agostino teaches students of the Morsani College of Medicine and the Department of Molecular Pharmacology and Physiology, with a focus on such topics as neuropharmacology, medical biochemistry, cell metabolism, and signaling. In his capacities as a researcher, Dominic D’Agostino enjoys support from the […]
In December of 2004, our 4 year old son Raffi was diagnosed with a brain tumor. After three surgeries and several failed drug protocols, it was clear that the tumor was winning. Raffi’s vision, language and motor skills deteriorated and a cascade of endocrine problems affected many vital functions. Our little fighter had done everything […]
The ketogenic diet is unique in its ability to simultaneously put cancer cells under metabolic stress while ‘supercharging’ normal cells capacity to deal with a variety of insults. Chemotherapy is responsible for numerous side effects that significantly detract from the patient’s quality of life, leaving people sick and exhausted. To date, few therapies have been […]
Glioblastoma Multiforme (GBM) is the most aggressive form of brain cancer. Median time of survival is about 15 months from diagnosis. Standard therapy for GBM includes surgical resection followed by concomitant radiation and chemotherapy and is able to extend GBM patients’ lives by approximately 1 year. Like all cancers GBM is highly dependent on glucose […]
Dr. Seyfried, other than Otto Warburg himself, may well be considered the godfather of the metabolic theory of cancer. In this video he briefly explains the main points of the metabolic theory of cancer, and the use of the ketogenic diet in managing brain cancer. Of special interest is the synergy between diet and 2-Deoxy-glucose, […]
The therapies that treat cancer as a metabolic disease exhibit incredible promise. The main stumbling block right now is that nobody knows how to make money from the molecules that treat cancer metabolically, because they are mostly non-patentable – so little attention gets paid. What follows is two case studies of cancer patients whom tried […]